infective endocarditis Queensland (ieQ)

ieQ logoieQ is a Prince Charles Hospital initiative to establish Australia’s first clinical and research collaborative supporting improved outcomes for patients with infective endocarditis.

Established in 2017, and facilitated by a Metro North SEED Grant and extensive clinician in-kind support, the collaborative has established a multi-faceted structural platform. In May 2018, the Collaborative received additional recognition and support from The Prince Charles Hospital Foundation “The Common Good”.

Affiliations

UQ logo

Pathology QLD logo

QLD Government logo

Supported by

The Common Good logo

 

LINK and SEED Innovation Funding
Clinical Operations & Strategic Implementation (COSI); Metro North Hospital and Health Service       

                  

About

Why?

Infective Endocarditis [IE] is a relatively rare condition in general practice, but is more common in cardiothoracic referral hospitals such as The Prince Charles Hospital. This condition affects dozens of Queenslanders per year, many requiring open-heart surgery. At least 1 in 10 Queenslanders with this disease will die from it and many more will suffer serious consequences affecting their quality of life. At TPCH, we admit and treat an estimated 60-80 patients with infective endocarditis every year.

Because of the relative rarity of this condition, little is actually known about it. All current guidelines are international, and none specific to Australia. Our leads, representing TPCH, are part of a global effort to expand knowledge about this condition.

How?

  • Under a clinical and research framework, ieQ aims to improve understanding, in an Australian context, of this disease.
  • By having an established expert working group across multiple disciplines, with an affiliated patient/consumer representative, we’ll optimise education, research and translational opportunities.
  • With a focus on parallel clinical engagement and provision of an Expert Advisory Team [initially localised to TPCH but planned to expand state-wide], we can support front-line, evidenced-based, patient care.
  • The enabling of the IE Registry and Biobank [HREC/15/QPCH/60] is the first of its kind in Australia, and is anticipated to provide a strong repository for a broad spectrum of future research endeavours, from biomarkers through to genetics, and epidemiology through to health service utilisation.

Download the ieQ flyer

Structure

ieQ structure

 

Our people

Chair:
Dr Robert Horvath MBBS FRACP FRCPA   
Infectious Diseases Physician and Clinical Microbiologist;
Infection Management services; The Prince Charles Hospital
 
Co-chair:
Dr John F Sedgwick MBBS FRACP FCSANZ FASE
Cardiolgist and Senior Staff Specialist, The Prince Charles Hospital
 
 
 
Principal Investigators:

Dr Robert Horvath MBBS FRACP FRCPA                                                                     

Dr John F Sedgwick MBBS FRACP FCSANZ FASE

Dr Joseph C Lee  FRACP                                                                                                    Clinical Director and Specialist Consultant Physician;                                                            Nuclear Medicine; Department of Medical Imaging; The Prince Charles Hospital

 Dr Yong S Wee MBBS FRACP
 Cardiologist, The Prince Charles Hospital
 
 

Dr David B Godbolt MBBS B.Med Sci FRCPA

Research Manager:
 Ms Anne Cameron RN 
 Internal Medicine Services, The Prince Charles Hosptial

 

 
Registrars/Advanced Trainees:

Dr Kanthi Vemuri

Infective Endocarditis Working Group:
Terms of Reference with current membership as of April 2018

 

Clinical guidelines and links

Australasian Society for Infectious Diseases

The Australasian Society for Infectious Diseases is the peak professional body for infectious diseases and microbiology in the region and a key stakeholder for government departments, medical colleges and other societies, including international organisations. Membership encompasses Infectious Diseases Physicians, Clinical Microbiologists, Scientists, Infection Control Practitioners, Public Health Physicians, Sexual Health Physicians, Veterinarians and others eminent in the field of infectious diseases. The aims of the society are to:

  • Advance postgraduate education in infectious diseases in Australasia and internationally;
  • Promote research in all aspects of infectious diseases; and
  • Advocate for sound and evidence-based public health policy in matters related to infectious diseases.

Cardiac Soicety of Australia and New Zealand

The Society was constituted with the objective of promoting the highest standards of education, training, research and practice in cardiovascular medicine and surgery through:

a. contributing to the advancement of knowledge of the cardiovascular system and treatment of diseases

b. establishing and supporting the maintenance of professional and ethical standards of practice 

c. facilitation of the education of trainees in cardiovascular medicine 

d. facilitation of continuing professional development in cardiovascular medicine 

e. promotion and defence of equitable access of all Australians and New Zealanders to high quality cardiovascular healthcare; and 

f. promotion of good fellowship among those whose primary interest is the practice of cardiovascular medicine or surgery or allied subjects.

International Society of Cardiovascular Infectious Diseases

ISCVID was founded in the late 1980s to bring scientific awareness to endocarditis, a disease of high morbidity and mortality but with very little organized multinational collaboration. In the early 1990s this society began holding biennial scientific sessions to bring together the community of endocarditis investigators.

American Heart Association

The American Heart Association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. Founded by six cardiologists in 1924, the AHA now includes more than 22.5 million volunteers and supporters. The AHA funds innovative research, fights for stronger public health policies, and provides critical tools and information to save and improve lives.
 Centre for Disease Control and Prevention      

The CDC works 24/7 to protect America from health, safety and security threats, both foreign and in the U.S. Whether diseases start at home or abroad, are chronic or acute, curable or preventable, human error or deliberate attack, CDC fights disease and supports communities and citizens to do the same.

As America's health protection agency, the CDC saves lives and protects people from health threats. To accomplish their  mission, the CDC conducts critical science and provides health information that protects against expensive and dangerous health threats, and responds when these arise.

Patient information

Content to come

ieQ projects

HREC/15/QPCH/60: Host Pathogen Relationships and improved diagnosis in Infective Endocarditis (IE)
HREC/16/QPCH/351: The Queensland Staphylococcus Lugdunensis Bacteraemia Audit
HREC/17/QPCH/469: The Queensland Staphylococcus Lugdunensis statewide molecular study

 

Conference and Meeting Abstracts

Australasian Society for Infectious Diseases

2018 affiliated abstracts:
  • ieQ: Establishment of Australia's first infective endocarditis Registry and Bio.bank. Robert Horvath, John F Sedgwick, Yong S Wee, Joseph C Lee, David B Godbolt and Anne Cameron, on behalf of the ieQ Collaborative.                                                                                                   Download
  • Not as pathogenic as we thought? The Queensland Staphylococcus lugdunensis Bacteraemia audit. Kanthi Vemuri, Madan Panda, Robert Horvath, Karen Hay, Graeme Nimmo, and on behalf of the ieQ Collaborative.                                                                              Download
  • Orthotopic Cardiac Transplantation for Chagas Cardiomyopathy in Australia. Koitka K, Lau K, Habibian M, Ulett K, McKenzie, S, Chan, W, Javorsky G, Wong YW, Thompson B, Pauli J, Horvath R, and Platts D.                                                                                                Dowload

 

Publications

2018

Mark R. Armstrong, Kate L. McCarthy & Robert L. Horvath (2018): A contemporary 16-year review of Coxiella burnetii infective endocarditis in a tertiary cardiac center in Queensland, Australia, Infectious Diseases, DOI: 10.1080/23744235.2018.1445279

 Dowload

2016

Bookchapter

J.F. Sedgwick and G.M. Scalia (Nov 2016): Advanced Echocardiography for the Diagnosis and Management of Infective Endocarditis. In: Contemporary Challenges in Endocarditis (Open Access Online), INTECH, pp. 59-94.

Open Access  

News and events


RESEARCH GRANT CEREMONY June1 2018

Project Development Grant Recipient: infective endocarditis Queensland Collaborative