Field:

  • Cardiology
  • Epidemiology
  • Public health

Location:  QIMR Berghofer (Herston)

Type of student:  Both types will be considered (i.e. flexible with project)

Type of work:

  • Chart reviews
  • Literature review
  • Statistical analysis

Heart transplantation is a life-saving measure for end-stage heart failure patients. It is also a massive investment by the community through the health care system and personally by donors’ families. However, the growing problem of weight gain after transplantation is eroding the life-saving potential of this procedure because post-transplant overweight and obesity exacerbate underlying cardiovascular disease, diabetes, risk of organ rejection and ultimately reduce survival. In addition, the subgroup of patients on the wait-list for transplant who need a ventricular assist device appear especially susceptible to rapid and excessive weight gain after device implantation but Australian data are lacking .

In this retrospective cohort study, we aim to describe the extent of changes in bodyweight after transplantation, and document cardiovascular biomarkers (e.g. blood pressure, blood lipids) among adult heart transplant recipients. We also plan to specifically study the patients with pre-transplant ventricular assist devices, the configuration of the ventricular assist device and duration on the ventricular assist device and weight gain.

This project would be suitable for Honours, Masters, or MPhil students.

Interested students should have a Health or Medical Science background. The project involved extraction of weight data from medical records and then supervised data analysis, so knowledge of statistics and experience with data analysis are both essential.

Prerequisite skills: Knowledge of statistics and experience with data analysis

 

Supervisor

Dr Kyoko Miura

Research Officer
QIMR Berghofer