Dr Ahmed Mehdi
JDRF Research Fellow
UQ Diamantina Institute
The University of Queensland Diamantina Institute
Researcher biography
| Featured projects | Duration |
|---|---|
| Predicting type-1 diabetes |
PhD and MPhil Supervision
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Journal Articles
Mehdi, Ahmed M., Hamilton-Williams, Emma E., Cristino, Alexandre, Ziegler, Anette, Bonifacio, Ezio, Le Cao, Kim-Anh, Harris, Mark and Thomas, Ranjeny (2018) A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes. JCI Insight, 3 5: . doi:10.1172/jci.insight.98212
Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Larrondo, Milton L., Aravena, Octavio, Molina, Mar-A C., Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2017) Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response. Frontiers in Immunology, 8 . doi:10.3389/fimmu.2017.01350
Ali, Rubbiya A., Mehdi, Ahmed M., Rothnagel, Rosalba, Hamilton, Nicholas A., Gerle, Christoph, Landsberg, Michael J. and Hankamer, Ben (2017) RAZA: A Rapid 3D z-crossings algorithm to segment electron tomograms and extract organelles and macromolecules. Journal of Structural Biology, 200 2: 73-86. doi:10.1016/j.jsb.2017.10.002
Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016) Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 OCT: . doi:10.3389/fimmu.2016.00458
Pang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015) Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 8: e41.1-e41.9. doi:10.1038/cti.2015.17
Benham, Helen, Nel, Hendrik J., Law, Soi Cheng, Mehdi, Ahmed M., Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Lee, Bernett T., Ng, Jennifer, Brunck, Marion E. G., Hyde, Claire, Trouw, Leendert A., Dudek, Nadine L., Purcell, Anthony W., O'Sullivan, Brendan J., Connolly, John E., Paul, Sanjoy K., Le Cao, Kim-Anh and Thomas, Ranjeny (2015) Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients. Science Translational Medicine, 7 290: 290ra87.1-290ra87.11. doi:10.1126/scitranslmed.aaa9301
Roona, Gergely, Borsos, Mate, Ellis, Jonathan J., Mehdi, Ahmed M., Christie, Mary, Koornyei, Zsuzsanna, Neubrandt, Mate, Tooth, Judit, Bozooky, Zoltan, Buday, Laszlo, Madaraasz, Emilia, Bodaen, Mikael, Kobe, Bostjan and Veertessy, Beata G. (2014) Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation. Cell Cycle, 13 22: 3551-3564. doi:10.4161/15384101.2014.960740
Mehdi, Ahmed M., Patrick, Ralph, Bailey, Timothy L. and Boden, Mikael (2014) Predicting the dynamics of protein abundance. Molecular and Cellular Proteomics, 13 5: 1330-1340. doi:10.1074/mcp.M113.033076
Mehdi, Ahmed M., Sehgal, Muhammad Shoaib B., Kobe, Bostjan, Bailey, Timothy L. and Boden, Mikael (2013) DLocalMotif: a discriminative approach for discovering local motifs in protein sequences. Bioinformatics, 29 1: 39-46. doi:10.1093/bioinformatics/bts654
Marfori, Mary, Mynott, Andrew, Ellis, Jonathan J., Mehdi, Ahmed M., Saunders, Neil F. W., Curmi, Paul M., Forwood, Jade K., Bodén, Mikael and Kobe, Bostjan (2011) Molecular basis for specificity of nuclear import and prediction of nuclear localization. Biochimica et Biophysica Acta (BBA): Molecular Cell Research, 1813 9: 1562-1577. doi:10.1016/j.bbamcr.2010.10.013
Mehdi, Ahmed M., Sehgal, Muhammad Shoaib B., Kobe, Bostjan, Bailey, Timothy L. and Boden, Mikael (2011) A probabilistic model of nuclear import of proteins. Bioinformatics, 27 9: 1239-1246. doi:10.1093/bioinformatics/btr121
Mehdi, Ahmed M., Zayegh, Aladin, Begg, Rezaul and Ali, Rubbiya (2010) GK based fuzzy clustering for the diagnosis of cardiac arrhythmia. International Journal of Computational Intelligence and Applications, 9 2: 105-123. doi:10.1142/S146902681000280X
Conference Papers
Law, Soi-Cheng, Nel, Hendrik, Mehdi, Ahmed, Le Cao, Kim-Anh and Thomas, Ranjeny (2014). Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.. In: Special Issue: 2014 ACR/ARHP Annual Meeting Abstract Supplemen. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, (S422-S422). 14-19 November 2014. doi:10.1002/art.38914
Raza, Muhammad Taskeen, Sheikh, Noor M., Fahiem, Muhammad Abuzar and Mehdi, Ahmed M. (2011). Performance of different approaches for predicting the subcellular locations of proteins: a review. In: Syed Misbahuddin and Mirza Imran Baig, 2011 IEEE 14th International Multitopic Conference (INMIC 2011). Proceedings. INMIC 2011: 14th IEEE International Multitopic Conference, Karachi, Pakistan, (90-95). 22-24 December, 2011. doi:10.1109/INMIC.2011.6151518
Mehdi, Ahmed M., Sehgal, Mohammad Shoabib, Zayegh, Aladin, Begg, Rezaul and Manan, Abdul (2009). K-Means Clustering on 3rd order polynomial based normalization of Acute Myeloid Leukemia (AML) and Acute Lymphocyte Leukemia (ALL). In: 2009 Third International Conference on Electrical Engineering (ICEE 2009). Proceedings. ICEE 2009: 3rd International Conference on Electrical Engineering, Lahore, Pakistan, (36-40). 9-11 April, 2009. doi:10.1109/ICEE.2009.5173170
Paracha, Zahir J., Mehdi, Ahmed M. and Kalam, Akhtar (2009). Computational analysis of sag and swell in electrical power distribution network. In: Power Engineering Conference, 2009. AUPEC 2009. Australasian Universities: Proceedings. AUPEC '09 : 19th Australasian Universities Power Engineering Conference : sustainable energy technologies and systems, Adelaide, SA Australia, (). 27 - 30 September 2009.
Thesis
Mehdi, Ahmed Murtaza (2013). Computational models of nucleo-cytoplasmic trafficking by integrating heterogeneous data PhD Thesis, Institute for Molecular Bioscience, The University of Queensland.