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Topical antibiotics for preventing surgical site infection in wounds healing by primary intention (Review)
Heal CF, Banks JL, Lepper PD, Kontopantelis E, van Driel ML
Cochrane Database of Systematic Reviews 2016, Issue 11. Art. No.: CD011426.
Surgical site infections (SSI) can delay wound healing, impair cosmetic outcome and increase healthcare costs. Topical antibiotics are sometimes used to reduce microbial contaminant exposure following surgical procedures, with the aim of reducing SSIs.
The primary objective of this review was to determine whether the application of topical antibiotics to surgical wounds that are healing by primary intention reduces the incidence of SSI and whether it increases the incidence of adverse outcomes (allergic contact dermatitis,
infections with patterns of antibiotic resistance and anaphylaxis).